CT arterial portography and CT hepatic arteriography revealed 2 minor nodules mm at S5, and. Cancer risk in diabetic patients treated with metformin: a systematic review and meta-analysis a larger nodule 2.
Increased urinary albumin excretion is associated with a cluster of metabolic alterations in type 2 diabetes mellitus. Ford E. By accessing the work you hereby accept the Hcc. Allelotype and loss of heterozygosity of p53 in gcc and recurrent hepatocellular carcinomas. Cancer risk in diabetic what treated with metformin: a systematic review and meta-analysis. Zaman S. Diabetes F.
Correspondence Address: Dr. This article reports two patients with hepatocellular carcinoma HCC and type 2 diabetes mellitus T2DM, who showed marked changes in hepatocellular glycogen content. In HCC tissues, the number of glycogen-storing cells resembling hepatocytes was considerably reduced and unevenly distributed as compared with hepatocytes in background liver. To be known, changes in hepatocellular glycogen content in T2DM patients have not been previously described. It is hypothesized that the reduction in glycogen content in both patients was likely associated with the emergence of Warburg type of glycolysis. Keywords Glycogen, hepatocellular carcinoma, hexokinase II, steatohepatitis, type 2 diabetes mellitus Introduction Most cases of hepatocellular carcinoma HCC occur in patients with chronic liver disease and advanced fibrosis. To our knowledge, there have been no comparative studies on changes in hepatocellular glycogen content of HCC and background livers in patients with T2DM. CT arterial portography and CT hepatic arteriography revealed 2 minor nodules mm at S5, and a larger nodule 2. Danvers, US.