Mackie, A. Keat, Poststreptococcal reactive arthritis: what is it and how do we know? To find out whether poststreptococcal reactive arthritis PSRA is a discrete, homogeneous clinical syndrome. One hundred and eighty-eight cases were identified. The age distribution was bimodal, with one peak in childhood and one peak in adulthood. Eighty-three per cent of streptococcal isolates were group A.
PSRA arthritis is additive and persistent, and can involve large joints, small joints, or the axial skeleton. PSReA is unresponsive to aspirin or other nonsterioidal medications. Advanced Search. Arthritis affecting hands and cervical spine is less common. However, these tests yield normal results in patients with only chorea, making this diagnosis tricky.
He worked as a first grade school teacher. The use of antibiotic therapy with penicillin is recommended for the treatment of the streptococcal infection, while antibiotic prophylaxis with penicillin, sulfadiazine, or erythromycin is recommended in order to prevent the recurrence of ARF. Arthritis Rheum. The link between strep infection and rheumatic fever isn’t clear, but it appears that the bacteria trick the immune system.