Vitamin B12 – found in many meat and dairy products and taken as a supplement for better brain function and to stave off anaemia – might alter the genetic make-up of facial bacteria, promoting rapid inflammation that’s been linked to the formation of pimples, according to a study. As many poor souls are well aware, acne isn’t just for teenagers. In fact, it affects most of us at some point in our lives, with an estimated 80 percent of people between the ages of 11 and 30 around the world experiencing a breakout at some point. The unluckiest of us will have to deal with the unsightly lumps and bumps well into our forties and fifties, and the worst part is that despite being an incredibly common affliction, scientists don’t actually know much about what causes acne and how to prevent or treat it. To investigate, Huiying Li, a molecular pharmacologist at the University of California-Los Angeles, and her team decided to focus on high levels of B12 as a possible culprit, based on research from the past six decades that’s linked it to higher instances of the condition. The first thing they did was identify the molecular pathway that produces vitamin B12 in the skin bacterium P ropionibacterium acnes, and compared it in people with good skin, and people with acne-prone skin. They found that the vitamin B12 biosynthesis pathway in P. Next, they wanted to test the effects of an increased intake of B12 from eternal sources on the levels of naturally produced B12 in these skin bacteria. They gathered 10 volunteers with clear, healthy skin, and asked them to receive a vitamin B12 injection.
To determine whether vitamin B12 supplementation in subject HL altered the gene expression of the skin microbiota with a profile similar to those observed in the acne patients, we clustered the P. Various diseases have been linked to the human microbiota, but the underlying molecular mechanisms of the microbiota in disease pathogenesis are often poorly understood. We then determined the expression level of each OGU in each sample. Pediatrics 51, —
Our beauty, lifestyle, and parenting content inspires, educates, and entertains real women who want real, candid answers to their questions. That means my vegan diet lacked B12 and I could feel it. I was lethargic, my brain power was low, and I was short-tempered. So I added it into my diet with foods fortified with B12 and the occasional oral supplement before I started with B12 injections. I was depressed and confused. I desperately wanted to figure out the cause.
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